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M3 - Recovery/Mass Builder

Part Number 15
M3 - Recovery/Mass Builder
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M3 Product Description M3 (Maximum Muscle Mass) is a state of the art formulation designed to primarily to enhance the development of muscle strength and mass throughout an intense strength training regimen. Additionally M3 can also be used to aid in recovery from intense endurance training. What makes M3 unique is that it uses components that address to three key issues associated with how an individual will respond to training by providing a metabolically favorable environment for muscle recovery and subsequent “super-compensation”. These are 1) minimizing the muscle inflammatory response and damage that occur during intense training, 2) providing the necessary amino acids used as building blocks for protein synthesis and that also play a role in stimulating protein synthesis, and 3) modifying the metabolic environment in favor of protein synthesis while reducing protein breakdown. The M3 special amino acid blend is formulated to provide the optimal amounts of precursor amino acids to maximize your response to training by stimulating protein synthesis while simultaneously reducing protein breakdown following intense training. Included in the M3 blend are three components that have clearly demonstrated anti-inflammatory, anti-oxidant and hormonal modulator effects. Exercise induced muscle damage immediately signals immune system cells to the muscle whereby they initiate inflammation and also generate reactive oxygen species (free radicals) that can interfere with recovery. 3,5,4'-Trihydroxystilbene (also known as resveratrol/trans-resveratrol) is a phenolic compound found naturally in fruits, nuts, flowers, seeds and bark of different plants. It exhibits a wide range of biological effects, including antiplatelet, anti-inflammatory, anticancer and antifungal properties. It is also a potent antioxidant, reactive oxygen species scavenger and metal chelator. Resveratrol reduces lipid peroxidation, thus preserving cell membrane integrity, and reduces oxidation of proteins. Resveratrol also stimulates NO (nitric oxide) production in association with the amino acid arginine to enhance blood flow to the muscle during and immediately following your workout. Polygonum cuspidatum is an herb used in traditional Chinese medicine that also has important recuperative and potentially anabolic properties P.cuspidatum has a demonstrated ability to interfere with the release of inflammatory mediators by activated neutrophils, the immune cells that respond to damaged muscle. In addition, P.cuspidatum may also have subtle modulating effects on the balance of testosterone and estrogen. There is evidence that resveratrol from P. cuspidatum is also a potent aromatase inhibitor. Aromatase is the enzyme that converts testosterone to estrogen. Testosterone-estrogen imbalance leading to overproduction of testostertone can inhibit muscle development. Thus it can help maintain adequate testosterone levels without inducing adverse effects. Also found in P. cuspidatum is emodin, a biologically active, naturally occurring compound with similar properties as resveratrol. From ancient times, emodin has been an active component in herbal extracts used for medical treatment. The third component is an extract derived from ant (Polyrachis). Ants are extremely rich in nutrients, including significant amounts of vitamins B1, B2, B12, D and E. Ant contains as much as 67% protein and provides 8 essential amino acids. It contains enzymes and other active substances. Ant has been widely used as both food and medicine in China for over 3000 years. Ants are rich in more than 20 trace elements such as magnesium, calcium, phosphorus, iron, selenium, and especially zinc. Current published research has verified these benefits, especially by demonstrating the potent anti-inflammatroy properties of Polyrhachis References: Bowers JL, Tyulmenkov VV, Jernigan SC, Klinge CM. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinology. 2000 Oct;141(10):3657-67. Coombes JS, McNaughton LR. Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise. J Sports Med Phys Fitness. 2000 Sep;40(3):240-6 Kimball SR, Jefferson LS. Control of protein synthesis by amino acid availability. Curr Opin Clin Nutr Metab Care. 2002 Jan;5(1):63-7. Review. Kou J, Ni Y, Li N, Wang J, Liu L, Jiang ZH. Analgesic and anti-inflammatory activities of total extract and individual fractions of Chinese medicinal ants Polyrhachis lamellidens.Biol Pharm Bull. 2005 Jan;28(1):176-80. Layman DK.Role of leucine in protein metabolism during exercise and recovery. Can J Appl Physiol. 2002 Dec;27(6):646-63. Manna SK, Mukhopadhyay A, Aggarwal BB. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J Immunol. 2000 Jun 15;164(12):6509-19. Medelli J, Lounana J, Hill D.Variation in plasma amino acid concentrations during a cycling competition. J Sports Med Phys Fitness. 2003 Jun;43(2):236-42 Mero A. Leucine supplementation and intensive training. Sports Med. 1999 Jun;27(6):347 Ryu G, Ju JH, Park YJ, Ryu SY, Choi BW, Lee BH The radical scavenging effects of stilbene glucosides from Polygonum multiflorum.Arch Pharm Res. 2002 Oct;25(5):636-9. Williams JZ, Abumrad N, Barbul A.Effect of a specialized amino acid mixture on human collagen deposition. Ann Surg. 2002 Sep;236(3):369-74; discussion 374-5 Yang PY, Almofti MR, Lu L, Kang H, Zhang J, Li TJ, Rui YC, Sun LN, Chen WS. Reduction of atherosclerosis in cholesterol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells by a water-soluble fraction of Polygonum multiflorum.J Pharmacol Sci. 2005 Nov;99(3):294-300. Epub 2005 Nov 8. Yi Chen (Charlie) Roger D. Alue, Ants Used as Food and Medicine in China Department of Entomology Washington State University Pullman WA 99164-6382
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